Grabbing Calf in Pain

High Cholesterol and Peripheral Artery Disease

High cholesterol occurs when there is an excessive amount of cholesterol, a waxy, fat-like substance, in the blood. Cholesterol is, however, necessary for building healthy cells, but too much of it can accumulate in the arteries, leading to plaque buildup. This plaque can harden over time and narrow the arteries, a condition called atherosclerosis, leading to peripheral artery disease (PAD).

One of the most common risk factors of PAD is high cholesterol. Cholesterol buildup in the arteries can lead to narrowing and blockages, limiting blood flow to the legs. Understanding the relationship between PAD and high cholesterol is important to managing and preventing this condition properly.

PAD Symptoms in High Cholesterol Patients

Patients with high cholesterol may experience symptoms of PAD earlier and have more severe symptoms due to plaque buildup. Common symptoms include:

  • Leg pain or cramping during physical activity
  • Numbness or weakness in the legs
  • Coldness in the lower foot or leg, especially when compared to the other side
  • A weak pulse or no pulse in the feet or legs
  • Hair loss or slower hair growth on the legs
  • Shiny skin on the legs

Diagnosing PAD in High Cholesterol Patients

Diagnosing PAD in individuals with high cholesterol typically involves a combination of diagnostic tests, medical history assessments, and physical examinations. Common diagnostic tests for PAD include:

  • Doppler Ultrasound: This test uses sound waves to visualize the blood flow in your arteries and detect blockages.
  • Angiogram: This imaging test involves injecting a contrast dye into the bloodstream to visualize the arteries and identify any narrowing or blockages.
  • Ankle-Brachial Index (ABI): This test compares the blood pressure in your ankle to the blood pressure in your arm to identify any reduced blood flow to the legs.

Prevention of PAD and High Cholesterol

Preventing PAD and managing high cholesterol involves making lifestyle changes and managing underlying conditions. Some preventative measures include:

  • Healthy Diet: A diet rich in fruits, vegetables, whole grains, and healthy fats (such as omega-3s) helps control cholesterol levels.
  • Regular Exercise: Physical activity for at least 30 minutes on most days can improve circulation and reduce cholesterol.
  • Quitting Smoking: Quitting smoking is one of the most effective steps to prevent PAD and cardiovascular disease.
  • Weight Management: Maintaining a healthy weight lowers cholesterol and reduces strain on the arteries.
  • Medications: Statins and other medications that lower cholesterol can help minimize plaque buildup in the arteries, lowering the risk of PAD.
PAD
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How Can High Cholesterol Lead to PAD?

High cholesterol plays a critical role in the development of PAD. Cholesterol, particularly low-density lipoprotein (LDL) or “bad” cholesterol, contributes to plaque formation on the arteries’ walls. Excess LDL cholesterol combines with fats, calcium, and other substances in the bloodstream to form plaque deposits along the inner walls of arteries. 

As plaque accumulates, the arteries narrow and stiffen, reducing the space for blood to flow through. This leads to reduced oxygen and nutrient supply to tissues, particularly in the legs. As the arteries become increasingly blocked, blood flow to the extremities is severely reduced, resulting in the classic symptoms of PAD, such as leg pain during walking (claudication) and non-healing wounds.

Genicular Artery Embolization
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What Happens When High Cholesterol and PAD Go Untreated?

Leaving PAD and high cholesterol untreated can lead to serious and potentially life-threatening complications. Without treatment, PAD tends to worsen over time. Restricted blood flow can lead to more frequent and severe symptoms, including debilitating pain and difficulty walking. In severe cases, PAD can result in critical limb ischemia, where the lack of blood flow leads to non-healing wounds, infections, and even tissue death (gangrene), which may require amputation.

High cholesterol leads to plaque buildup in arteries throughout the body, not just in the legs. Untreated high cholesterol increases the risk of heart attacks and strokes due to blockages in the arteries that supply the heart and brain. Individuals with PAD are at a significantly higher risk for these cardiovascular events.

PAD Treatments for High Cholesterol Patients

If lifestyle changes and medications haven’t worked, you may need a minimally invasive procedure to help treat PAD due to high cholesterol. American Endovascular provides various minimally invasive, image-guided PAD treatment options that help restore blood flow, prevent complications, and reduce symptoms.

  • Atherectomy: This procedure involves removing plaque from the artery using a tiny cutting device, allowing blood to flow more easily.
  • Angioplasty: During this procedure, a balloon is inflated inside the artery to widen it, improving blood flow.
  • Stent Placement: A small mesh tube, or stent, is inserted in the artery to keep it open after an angioplasty.

High Cholesterol Frequently Asked Questions

Can high cholesterol cause PAD?

Yes, high cholesterol is a major risk factor for PAD. It adds to plaque buildup in the arteries, leading to narrowing and blockages that limit blood flow.

How long does it take for PAD to develop with high cholesterol?

It varies from person to person and depends on lifestyle, genetics, and overall health. People with long-term, unmanaged high cholesterol, however, are at greater risk of developing PAD earlier in life.

What is the best way to manage high cholesterol and prevent PAD?

The most effective way to prevent PAD is to manage high cholesterol through a mix of regular exercise, a healthy diet, and medications.

Vascular Specialists in NY & NJ

At American Endovascular, we specialize in treating PAD with minimally invasive procedures. Our team of vascular specialists offers comprehensive care, from risk factor evaluation to advanced treatment options. Find one of our vascular specialists in NY & NJ.

Vascular Centers in New York and New Jersey

We operate several vascular centers in New York and New Jersey, providing advanced treatments for PAD. Our convenient locations ensure that you have expert care close to home.

Brooklyn, NY
71 Carroll Street
Brooklyn, NY 11231
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Harlem, NY
505 East 116th Street
Harlem, NY 10029
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Queens, NY
30-30 Northern Blvd
Suite 501
Queens, NY 11101
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West Orange, NJ
347 Mount Pleasant Avenue
Suite 100
West Orange, NJ 07052
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What Our Patients Are Saying

Dr. Shams Such a amazing vascular Surgeon knows him a little while, he knows exactly what should be done to makes everything better, I’m very satisfied with my procedure and also his work ethic, the vascular office included everything inside is a 5 Star luxury, thank – you to all the staff . MoniqueV Francois.
MoniqueV Francois
MoniqueV Francois
18:02 24 Mar 25
Looking forward to my next appointment!
Deborah “Debbie”
Deborah “Debbie”
21:17 04 Mar 25
Dr shams is amazing along with his team they make you feel at home.
Angela Poueriet
Angela Poueriet
15:19 27 Feb 25
Excellent consultation. Answered all questions.
Nichelle Abney
Nichelle Abney
20:39 25 Feb 25
Excelente Dr y su equipo medico, información claro que lo que a uno como paciente está experimentado altamente recomendado
A ñ Ivan Yanez
A ñ Ivan Yanez
17:51 13 Feb 25
I Just Love The Doctors And All The People Friendly Staff. Everyone is Caring, Warm, Personable And Professional. They Are The Best🩷
Shirley Monroe
Shirley Monroe
02:00 04 Feb 25
Excellent work
Javier Acevedo
Javier Acevedo
16:34 17 Jan 25
I Like The Doctor and all his Staff, everyone in the Office where Very Professional
Dolphus Fudge
Dolphus Fudge
18:28 04 Dec 24
Love this Dr and staff. They are all kind courteous and professional with excellent medical care. I would highly recommend them to anyone in need.
Sybil Wilkins
Sybil Wilkins
13:05 05 Sep 24
Professional and friendly from my phone call to make an appointment to my visit I felt I was is safe hands not just a number. Everyone was knowledgeable and explained the procedures.
James Mullen
James Mullen
19:47 17 Aug 24
Dr David Mobley was kind right to the point. Explained & solved my issue. The whole staff is professional.
Lizette
Lizette
17:52 03 Aug 24
It’s personal
Ricot Charlot
Ricot Charlot
10:57 03 Jul 24
Sheer perfection. The care and expertise and teamwork are the best I have ever experienced. I’m a former nurse and I recognize and give a shout out to the best!!!!
Barbara Murray
Barbara Murray
16:22 02 May 24
First Impressions are lasting impressions! First, the staff are phenomenal! How is it possible that each and every one of them are incredibly kind, caring, professional, personable and treat you like you are THE most important person in the world!? Well, meet this team for an experience that will make you feel valued as a person, not just as a patient. In walks this amazing Doctor and now you understand why his team are the way they are! They regard each other with the utmost respect, and kindness, and they communicate with each other like family. And as a new patient, I had the honor and pleasure to experience excellence in patient care and concern. I am so very grateful to have found a Doctor who is in my opinion perfect with a team who are exceptional! I’m excited for my next visit, honestly! I write this with a great big Smile on my face!
CC
CC
14:57 24 Apr 24
EXCELLENT, EXCELLENT, EXCELLENT ALL AROUND!!! THANK YOU!!!
Marion Moore
Marion Moore
13:44 17 Apr 24
Excellent, professional, organized and efficient all best describes the service here.
Delsi Cunningham
Delsi Cunningham
17:28 05 Apr 24
Very nice and friendly staff.I was so nervous, they all made me feel relaxed and comfortable.They explained everything to me step by step.
Keith Dickens
Keith Dickens
13:10 02 Apr 24
Excelente servicio es lo mejor que me a pasado gracias a sus buenos tratamiento ya no tengo dolor
The staff are the best. Very elated,with the exceptional care,professionalism, and genuine concern, displayed by all the staff.
Constance Sidberry
Constance Sidberry
03:50 17 Mar 24
I felt very comfortable with him. Excellent bedside manner, proper teaching , and knowledgeable. I highly recommend him!
Jamel Jackson
Jamel Jackson
14:07 27 Feb 24
Yes it was a good place
Carmen Diaz
Carmen Diaz
14:22 20 Feb 24
The absolute BEST Dr!! Detailed, caring & kind! The best medical procedure I’ve ever had from consultation to post procedure, perfect! 10s all around 👏🏽👍🏽👍🏽 many thank yous🙏🏾
Josi W
Josi W
22:04 12 Jan 24
Is good to be with friendly and professional staff at doctor’s offices like this one.
Dr. Joseph Sham and the entire Team were very professional, knowledgeable, informative and had incredible patience with me by answering all my questions and concerns. Great Team…Thank you all! 👍
Marion
Marion
22:17 27 Dec 23
I was treated very well. The staff was very professional and made me feel comfortable. Looking forward to my next visit.
Stephen Lapinsky
Stephen Lapinsky
20:17 20 Dec 23
This experience was great I’m so happy with everything
stephanie suazo
stephanie suazo
22:53 13 Dec 23
I love this place stuff is helpful an they all were nice. I had a wonderful experience Dr Shams was great.
Victoria Pacheco
Victoria Pacheco
22:07 17 Nov 23
Professional services
Ricky Mo
Ricky Mo
22:14 15 Nov 23
I like the doctor they were kind of pretty thorough he says that he could help me he found out the filter in my abdomen from the surgery I had in 1996 has been clogging my blood flow for 25 years and that’s causing the swelling at every other doctor told me was lymphedema it was not lymphedema it caused the lymphedema because no other doctor took the time or care enough to find out the reason for my leg swelling this doctor was the only one who finally found out and he’s going to see if you could put a stent inside the filter to open it up and and stop my legs from swelling hopefully this will all go good it hasn’t happened yet but I’ll keep you posted thankful for this docto I just pray and hope that it works otherwise I like the doctor very much
Mitchell Dedios
Mitchell Dedios
21:01 27 Oct 23
Excellent service , good customer service and friendly staff. Thanks
Raysa Polanco
Raysa Polanco
20:54 27 Oct 23
You may likely have to wait. Avoid anxiety and frustration. Schedule extra time for the visit. Allow for personal attention to your care needs once in the examination room. Friendly, nice staff and doctor puts you at ease. Bottom line: worth the wait!
Sisle
Sisle
21:49 26 Oct 23
Excellent service and staff i’ll let you feel relaxing and comfortable
kadine campbell
kadine campbell
21:01 23 Oct 23
I was given good advice about my blood circulation
Emma Bb
Emma Bb
17:04 08 Oct 23
Dr. Shams office is amazing. Whitney and Angela were AMAZING. Great sense of humor. Staff is WONDERFUL.
Sara Correa
Sara Correa
21:13 18 Sep 23
Nice office, personnel friendly, & caring, good informative information concerning my care.
Loretta Johnson
Loretta Johnson
21:26 22 Aug 23
Really like this doctor, talks in your language, just over all regular nice person.
Linda Thoomey
Linda Thoomey
22:03 21 Jul 23
I’m very satisfied of my visit for the first time, everyone was concerned about me, and Dr David was very patient to listen to my long health stories, after that He gave me good explanation for my problem, that was great 👍
Claude Jean Pierre
Claude Jean Pierre
22:38 18 Jul 23
Follow up to a procedure. Dr Mobley and his staff are great and always helpful
DanLiza Diehl
DanLiza Diehl
21:25 10 Jul 23
David monkey,MD and the grupo are excellent very kind and helpful.i will return to them.the attention.its very satisfied.thank u ..
Luis Sarria
Luis Sarria
12:16 29 Jun 23
I had a good experience with my procedure and Dr. Mobley’s follow-up calls are great. I’ve never had a doctor who has been so concerned about following up after a procedure to see how I’m doing and if there are any post-procedure problems I may have experienced (which there aren’t). I’d highly recommend Dr. Mobley.
Hey Beej
Hey Beej
16:42 23 Jun 23
Dr Mobley was so helpful, informative and made me feel secure in making my future medical plan. Supportive and kind. Highly recommended.
Amanda L Browder
Amanda L Browder
15:57 23 Jun 23
Doctor was very thorough. Explaining what the procedure is all about. Tell me what I could realistically expect. Couldn’t have asked for a better consultation. Highly recommended if you have a prostate issue
John Buric
John Buric
16:26 15 Jun 23
I was very pleased and satisfied on how Dr. David Mobley examined me and explained everything on what I need to know regarding my condition. He’s very professional and knowledgeable in all aspects of his profession. I would highly recommend him to my other friends!
Celine Parcon
Celine Parcon
23:16 07 Jun 23
Dr Shams was very attentive and explained everything in detail. The staff was very nice, the staff/nurse were all so very helpful, It was a Monday morning and I didn’t expect such happy staff.
Stacy Lebeau
Stacy Lebeau
21:22 06 Jun 23
He puts his patients before himself, returning calls and e-mails quickly. Not only is he kind and considerate, he is an excellent physician. I had to have a procedure that requires me to be awake, and he talked me through it and kept me at ease. If I could give him more stars, I would.
Super friendly, tentative, once in the procedure rm the sx staff made you feel comfortable, easy,+ answered all questions. David mobley, MD answered all my questions, very informative, caring. I felt confident in his care
Thais Bini
Thais Bini
21:22 30 May 23
Great doctor. Everyone is so kind and caring. Great place to go
Joan Jurica
Joan Jurica
14:46 30 May 23
Good service!
Veronika Shopina
Veronika Shopina
21:09 24 May 23
There is a friendly atmosphere, fast medical attention and an advanced medical equipment !!!The Staff is very knowledgeable and the best care possibly !!!100 % Satisfied !!!
Cruz Figueroa
Cruz Figueroa
03:06 08 May 23
Whole staff was very friendly and professional. I feel confident that I came to the right place for treatment.
Rudy Padilla
Rudy Padilla
02:08 13 Apr 23
The best in Astoria I recommend Dr mobley and staff 100 percent
michaela1951
michaela1951
21:25 30 Mar 23
Knowledgeable , experienced, great bed side manners
mohamed hamed
mohamed hamed
10:09 30 Mar 23
I am pleased w/my experience @ endovascular. I hope they can save my foot.
Margo A Williams
Margo A Williams
19:19 29 Mar 23
This has been the best medical experience I’ve had in over thirty years. I was nervous to have a procedure after only knowing about my condition a year ago. They made this process so easy for me that I’m in shock that I had no pain, no discomfort thanks to an excellent doctor and professional staff! Thank you all and best of luck to your practice.
Stacey Marius
Stacey Marius
14:16 29 Mar 23
The doctor was very nice and professional. He explained the tests that I need and why I need them.
Judith AndersonNeal
Judith AndersonNeal
22:12 27 Mar 23
This was the best experience I have had in such a long time and I have had quite a few procedures in the past both in patient and out including the procedure I was currently present for. No other surgeon has been so kind, transparent, and gentle. Not only did he personally come out beforehand to provide me with education on my procedure, but he talked me through every step of the way and made me feel so comfortable and relaxed. Not to mention his amazing staff! Despite being extremely nervous they kept me smiling and laughing throughout the whole process. 10/10 would recommend. Thank you so much guys!!
Riah L.
Riah L.
13:49 22 Mar 23
Excellent bedside manners and the procedure was a breeze.
sen-pei hsia
sen-pei hsia
18:26 20 Mar 23
Los mejores/ the best💖🙏
Ruthy Ochoa
Ruthy Ochoa
04:17 03 Mar 23
Excellent, Patience, don’t Rush you to be finished. The Doctor explains everything and answers your questions. I would Recommend Dr.Sham service anytime, they are. Great!
Debra Farmer
Debra Farmer
00:16 01 Mar 23
I went with my mom who just had a hip surgery. The whole team was very caring, nice and very professional. I did appreciate that the surgeon took the time to explain to me what was wrong with my mom’s arm and what he did to fix it.
mouna khalyat
mouna khalyat
14:37 24 Feb 23
Very good and very responsive.
James Young
James Young
19:33 22 Feb 23
Although I didn’t meet with the doctor, the receptionist, assistant and nurse were great.
Theresa Gaines
Theresa Gaines
13:25 13 Feb 23
Every thing and the process are being done properly ..Terissa you are very Carey ..thank you so much every body are very polite and very professional.. Thank you so much to Dr.Mobley..God blessed you all .🙏🙏🙏👍
Remigio Ruda
Remigio Ruda
03:28 31 Jan 23
Very knowledgeable, personable and professional. I came to Dr. Mobley to correct another surgeons work and I was pleased with the outcome. There is a Hispanic woman that runs things in the O.R.She is great! The whole staff is wonderful and caring.Highly recommend
Lakesha Kingdom
Lakesha Kingdom
15:57 17 Jan 23
I had a wonderful PA take care of me, & the nurses were very sweet. I was happy with my visit
Aurora Anello
Aurora Anello
19:20 10 Jan 23
Everything always goes well.staff are very caring.
Lillian Rodriguez
Lillian Rodriguez
19:00 11 Dec 22
Excellent Doctor he explains the procedure process so that it is understandable and comfortable for the patient!
T. J.
T. J.
14:48 06 Dec 21
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