What is Peripheral Artery Disease?

Peripheral Artery Disease (PAD) is a circulatory system condition caused by the gradual buildup of cholesterol plaque in the arteries. Though PAD can occur anywhere in the endovascular system, it frequently occurs in the legs. Over time, the accumulation of plaque—a combination of cholesterol, fat, calcium, and other substances coursing through the bloodstream—on the walls of the arteries can cause them to narrow. 

As a result, it becomes more difficult for blood to freely flow to the legs and feet. Often patients with peripheral artery disease have a much higher risk of developing serious health problems, including heart attack, stroke, or even amputation. Peripheral Artery Disease is common and treatable. The key is recognizing the warning signs so PAD can be treated early before it progresses.

PAD Senior Woman Leg Pain
Symptoms of Peripheral Artery Disease

In the early stages, 66% of all PAD patients have NO Symptoms. Typically, symptoms won’t appear until your arteries narrow by 70%, or until you experience claudication. It’s important to know the signs and symptoms of peripheral artery disease so you can catch it early and prevent it from becoming worse later on. 

PAD Symptoms

  • Leg Pain
  • Leg Discoloration
  • Leg Numbness
  • Leg Weakness
  • Non-Healing Foot Wounds
  • Poor Circulation

Risk Factors of Peripheral Artery Disease

An estimated 8.5 million people have peripheral artery disease in the United States. Women and men are both affected by PAD, but African Americans have approximately twice the risk of PAD as Caucasians or Asian Americans. A better understanding of peripheral artery disease risk factors can help you make lifestyle changes to reduce your chances of developing the disease.

PAD Risk Factors

  • Age Above 50 years
  • Diabetes
  • High Blood Pressure/Cholesterol
  • History of Vascular Disease
  • Kidney Disease
  • Obesity
  • Race
  • Smoking
PAD Older Woman Massaging Leg Cramp
Peripheral Artery Disease Causes

The main cause of peripheral artery disease is atherosclerosis, which is a health condition that causes the narrowing of arteries due to a plaque buildup. Atherosclerosis can also cause the arteries to become blocked, resulting in not enough blood, oxygen, or nutrients to travel to the legs or feet. There are also less common causes of PAD that may lead to the disease, involving injury, inflammation, or exposure to radiation.

Causes of PAD

  • Atherosclerosis
  • Blood Vessel Inflammation
  • Injury to the Legs
  • Leg Weakness
  • Muscles or Ligament Changes
  • Radiation Exposure
PAD
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Stages of Peripheral Artery Disease

There are four different stages of PAD. Your vascular specialist will determine if you have any of the following stages at the time of your screening. 

Asymptomatic

Not everyone experiences symptoms of PAD in the early stages. Patients during the first stage do not have symptoms even though the disease may keep progressing unnoticed until symptoms occur.

Claudication

Stage two of PAD is claudication. Patients during this stage begin to feel discomfort and pain in their lower extremities, which can occur during any type of exercise and go away after the patient rests.

Critical Limb Ischemia

The third stage of PAD is known as Critical limb ischemia (CLI), which severely reduces the blood flow to the extremities. During this stage, patients feel intense pain in the legs and feet even while resting (without any activity such as sitting in a chair, laying down or when sleeping).

Acute Limb Ischemia

Acute Limb Ischemia (ALI) is the final stage of PAD, involving the sudden loss of blood to the lower extremities. At this stage, patients can experience significant pain and their limbs can rapidly deteriorate and turn cold and pale -(which can lead to) leading to paralysis, amputation, or sometimes death.

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Peripheral Artery Disease Diagnosis

There are multiple ways to diagnose PAD. One of our affiliated specialists will perform a physical examination, review your medical history, and assess your risk factors. They may order different noninvasive tests to help diagnose the disease and determine its severity.

PAD Diagnostic Tests

  • Ankle-Brachial Index (ABI)
  • Angiography
  • CT Angiography
  • Blood Tests
  • Duplex Ultrasonography
  • Magnetic Resonance Angiography (MRA)

Peripheral Artery Disease Treatment

The American Endovascular affiliated team of vascular specialists is at the forefront of the detection and treatment of PAD. They have a proven track record of success at preventing the progression of PAD, saving the limbs that others can’t. Their array of minimally invasive-image guided treatment options can restore blood flow and get you on the road to a healthier life.

Amputation Prevention

Using advanced techniques and technologies, such as pedal loop interventions, our affiliated physicians help with limb salvage and preservation in patients with non-healing wounds due to peripheral artery disease.

Angioplasty

Angioplasty uses a low-profile catheter with an inflatable balloon to stretch the affected artery open. The primary goal of the procedure is to restore blood flow to the clogged artery and increase oxygen-rich blood to the body’s muscles and tissues.

Atherectomy

An atherectomy involves removing plaque from arteries with a catheter via a minimally invasive incision. This procedure has evolved with cutting-edge advances, including orbital, rotational, and diamond-coated surface technology, as well as a laser to remove or modify plaque from a clogged blood vessel.

Stent Placement

Stents are a host of different metallic-based implantable devices inserted into the artery to provide a new skeletal framework to strengthen the walls and help it remain open. Some stents may have drug-eluting properties to prevent blood clotting and increase longevity.

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What to Expect from
Your PAD Treatment

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Less Invasive
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Same Day Procedure
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No Hospital Stay
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Shorter Recovery Time

Peripheral Artery Disease FAQ

What is Considered the First Symptom of Peripheral Artery Disease?

The first symptom of PAD is generally leg, calf or foot pain during physical activity, such as walking, that gets better after you rest. You may experience pain, aches, or cramping in your thighs or calves or feet during your walk, which may be a sign of PAD.

What is the Biggest Risk Factor for Peripheral Artery Disease?

Smoking is the most common risk factor for PAD. 80% of people who smoke tobacco or used to smoke have PAD. Smoking can bring on PAD symptoms almost 10 years earlier and significantly increase the risk of the disease due to causing impaired blood flow in the body.

Can Peripheral Artery Disease Be Reversed?

Peripheral arterial disease is reversible in the earlier stages. You can reverse PAD symptoms by controlling your cholesterol and blood pressure levels with medication and through lifestyle changes such as diet, exercise, or quitting smoking.

Our Vascular Specialists

American Endovascular is proud to be affiliated with vascular specialists in NY that represent the “best of the best.” Our affiliated physicians at our vascular centers are nationally recognized as innovators and leaders in vascular and interventional radiology, providing high-quality and compassionate care for our patients living with PAD.

Our Vascular Centers in NY

American Endovascular has vascular centers in New York. Each of our centers is equipped with the latest minimally invasive-image guided technology that offers patients streamlined care in an outpatient setting.

Brooklyn, NY
71 Carroll Street
Brooklyn, NY 11231
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Harlem, NY
505 East 116th Street,
2nd Floor
Harlem, NY 10029
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Queens, NY
30-30 Northern Blvd
Suite 501
Queens, NY 11101
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What Our Patients Are Saying

Love my visits smooth best vascular doctor
Charmaine Lawrencr
Charmaine Lawrencr
13:01 07 Mar 26
Good service; one of my family members needed an angioplasty done. The medical professionals were very thorough and explained the entire process, along with following up a couple of days afterwards to see how things were.
Charles Brewster Jr
Charles Brewster Jr
22:16 23 Feb 26
Very Professional and Caring Environment. Without any hesitation, I would recommend the Endovascular Center of Harlem.
Nikki
Nikki
22:25 10 Feb 26
Very professional. Kept me informed through the procedure.
Laurence Clarke
Laurence Clarke
21:55 28 Jan 26
P very smooth cool and pleasant experience
Peter Handras
Peter Handras
22:34 22 Jan 26
I didn’t have to wait long to see Dr Shams he checked my wound and everything looked good the nurses were very efficient and took good care of me
Lynn Brightman
Lynn Brightman
16:56 18 Jan 26
I cannot say enough great things about Dr. Joseph N. Shams and his entire team. From the moment you walk into his office, you are treated with genuine care, respect, and professionalism that truly sets this practice apart. Dr. Shams is not only extremely knowledgeable and thorough, but he also takes the time to actually listen to his patients. He explains everything clearly, answers questions patiently, and makes sure you feel comfortable and confident every step of the way.What truly makes this office exceptional is the team of nurses and staff who work alongside him. Every single person you encounter is kind, attentive, and welcoming. The nurses go above and beyond to make sure patients feel cared for, never rushed, and always supported. You can tell they genuinely love what they do, and that positive energy carries throughout the entire office.Appointments are well-organized, wait times are reasonable, and the overall environment is clean, calm, and professional. It’s rare to find a medical office where every single staff member consistently delivers such a high level of service, but Dr. Shams and his team manage to do exactly that.If you’re looking for a doctor who truly puts patients first and an office where compassion and excellence are the standard, not the exception, I highly recommend Dr. Joseph N. Shams and his incredible staff. This is healthcare done the right way.
Ken C
Ken C
03:00 16 Jan 26
Excellence all around. The doctor clearly explained the treatment and what was to be expected during recovery phase of healing.I am pleased with the outcome.The facility was clean, and the staff were very friendly. I highly recommend the. Thanks.
J B
J B
16:15 19 Dec 25
The visit was great good service from everyone staffs / doctors very professional and on time I will give a 10+
Linda Noriega
Linda Noriega
23:06 25 Nov 25
Dr. Shan is a blessing sent from god. After seeing him my leg/ feet swelling was down. After being on my feet for hours. The staff were all attentive very professional. Answered any questions and concerns I had at the time. The entire team was great. I am so pleased I did my research and change Vascular doctors. You guys are all great. You make your patients fell welcome. Keep doing what you guys are doing. God bless you all.
Tina McLaughlin
Tina McLaughlin
05:52 18 Nov 25
Outstanding. Kindness, patience and excellence. Im doing well.
Deborah Moss
Deborah Moss
15:03 14 Nov 25
Dr Shams is a wonderful n caring person so is his whole staff.
Ana Rosario
Ana Rosario
17:20 12 Nov 25
I am walking much better than before and I’m not walking with a cane no more so Dr. Sam did a pretty good job on me. Thank you, Dr. sham
Sharon Gy
Sharon Gy
22:23 10 Nov 25
He show unusual compassion and skill. I was soo nervous but the center’s team & DR was Excellent!
Verian Evans-Pimble
Verian Evans-Pimble
21:16 23 Oct 25
Dr. Shams Such a amazing vascular Surgeon knows him a little while, he knows exactly what should be done to makes everything better, I’m very satisfied with my procedure and also his work ethic, the vascular office included everything inside is a 5 Star luxury, thank – you to all the staff . MoniqueV Francois.
MoniqueV Francois
MoniqueV Francois
20:55 23 Oct 25
The staff and the doctor were very professional and treated me with the best care possible.
Sargent Rivera
Sargent Rivera
20:56 17 Oct 25
The best vascular doctor in the tri state area and a good friend
Darryl Jacobs
Darryl Jacobs
05:25 03 Sep 25
Staff and Dr. shams very friendly made me feel at ease. Explained to me what was wrong and what needed to be done so that I can understand.
Debra Santos
Debra Santos
22:16 02 Sep 25
Everything was perfect and professional. I am feeling fine and delighted with the results
Fred Spinowitz
Fred Spinowitz
22:12 02 Sep 25
It was great the service hope it continues
Joanna Morales
Joanna Morales
17:43 14 Aug 25
Wonderful visit. He really is the best. Do not have e to wait long a day he takes his time.
Cynthia J
Cynthia J
18:36 31 Jul 25
Dr Shams is good!!!!
David Forbes
David Forbes
18:48 24 Jul 25
I found that both the doctors and staff to be complete professionals in their practice
George Greene
George Greene
18:59 11 Jun 25
Was treated very nice by the personal
Milton williams
Milton williams
19:56 03 Jun 25
Very good staff. Did not have to wait to see the doctor.
Moises Cuevas
Moises Cuevas
01:19 23 May 25
I WENT TO THE DOC, TO EXPLAIN MY ISSUES AND I LEFT FEELING BETTER THAN WHEN I WENT IN. THANK YOU DOC
Nesamiah B
Nesamiah B
20:44 06 May 25
It 1 thing to to know. The GOD HAS many to show great work. Thank you staff. I feel good . That there is feed back .Thank Angels for showing the Grace of GOD IS AT. HERE AT. PLACE.
Patt Craig
Patt Craig
20:55 23 Apr 25
Looking forward to my next appointment! Best care I’ve had in many
Deborah “Debbie”
Deborah “Debbie”
19:40 23 Apr 25
Staff, Dr Sham super 10plus
Roger Mojer
Roger Mojer
17:20 02 Apr 25
Excellent consultation. Answered all questions.
Nichelle Abney
Nichelle Abney
20:39 25 Feb 25
Excelente Dr y su equipo medico, información claro que lo que a uno como paciente está experimentado altamente recomendado
A ñ Ivan Yanez
A ñ Ivan Yanez
17:51 13 Feb 25
I Just Love The Doctors And All The People Friendly Staff. Everyone is Caring, Warm, Personable And Professional. They Are The Best🩷
Shirley Monroe
Shirley Monroe
02:00 04 Feb 25
Excellent work
Javier Acevedo
Javier Acevedo
16:34 17 Jan 25
I Like The Doctor and all his Staff, everyone in the Office where Very Professional
Dolphus Fudge
Dolphus Fudge
18:28 04 Dec 24
Love this Dr and staff. They are all kind courteous and professional with excellent medical care. I would highly recommend them to anyone in need.
Sybil Wilkins
Sybil Wilkins
13:05 05 Sep 24
Professional and friendly from my phone call to make an appointment to my visit I felt I was is safe hands not just a number. Everyone was knowledgeable and explained the procedures.
James Mullen
James Mullen
19:47 17 Aug 24
It’s personal
Ricot Charlot
Ricot Charlot
10:57 03 Jul 24
Sheer perfection. The care and expertise and teamwork are the best I have ever experienced. I’m a former nurse and I recognize and give a shout out to the best!!!!
Barbara Murray
Barbara Murray
16:22 02 May 24
First Impressions are lasting impressions! First, the staff are phenomenal! How is it possible that each and every one of them are incredibly kind, caring, professional, personable and treat you like you are THE most important person in the world!? Well, meet this team for an experience that will make you feel valued as a person, not just as a patient. In walks this amazing Doctor and now you understand why his team are the way they are! They regard each other with the utmost respect, and kindness, and they communicate with each other like family. And as a new patient, I had the honor and pleasure to experience excellence in patient care and concern. I am so very grateful to have found a Doctor who is in my opinion perfect with a team who are exceptional! I’m excited for my next visit, honestly! I write this with a great big Smile on my face!
CC
CC
14:57 24 Apr 24
EXCELLENT, EXCELLENT, EXCELLENT ALL AROUND!!! THANK YOU!!!
Marion Moore
Marion Moore
13:44 17 Apr 24
Excellent, professional, organized and efficient all best describes the service here.
Delsi Cunningham
Delsi Cunningham
17:28 05 Apr 24
Very nice and friendly staff.I was so nervous, they all made me feel relaxed and comfortable.They explained everything to me step by step.
Keith Dickens
Keith Dickens
13:10 02 Apr 24
Excelente servicio es lo mejor que me a pasado gracias a sus buenos tratamiento ya no tengo dolor
The staff are the best. Very elated,with the exceptional care,professionalism, and genuine concern, displayed by all the staff.
Constance Sidberry
Constance Sidberry
03:50 17 Mar 24
I felt very comfortable with him. Excellent bedside manner, proper teaching , and knowledgeable. I highly recommend him!
Jamel Jackson
Jamel Jackson
14:07 27 Feb 24
The absolute BEST Dr!! Detailed, caring & kind! The best medical procedure I’ve ever had from consultation to post procedure, perfect! 10s all around 👏🏽👍🏽👍🏽 many thank yous🙏🏾
Josi W
Josi W
22:04 12 Jan 24
Is good to be with friendly and professional staff at doctor’s offices like this one.
I was treated very well. The staff was very professional and made me feel comfortable. Looking forward to my next visit.
Stephen Lapinsky
Stephen Lapinsky
20:17 20 Dec 23
This experience was great I’m so happy with everything
stephanie suazo
stephanie suazo
22:53 13 Dec 23
I love this place stuff is helpful an they all were nice. I had a wonderful experience Dr Shams was great.
Victoria Pacheco
Victoria Pacheco
22:07 17 Nov 23
Professional services
Ricky Mo
Ricky Mo
22:14 15 Nov 23
I like the doctor they were kind of pretty thorough he says that he could help me he found out the filter in my abdomen from the surgery I had in 1996 has been clogging my blood flow for 25 years and that’s causing the swelling at every other doctor told me was lymphedema it was not lymphedema it caused the lymphedema because no other doctor took the time or care enough to find out the reason for my leg swelling this doctor was the only one who finally found out and he’s going to see if you could put a stent inside the filter to open it up and and stop my legs from swelling hopefully this will all go good it hasn’t happened yet but I’ll keep you posted thankful for this docto I just pray and hope that it works otherwise I like the doctor very much
Mitchell Dedios
Mitchell Dedios
21:01 27 Oct 23
Excellent service , good customer service and friendly staff. Thanks
Raysa Polanco
Raysa Polanco
20:54 27 Oct 23
You may likely have to wait. Avoid anxiety and frustration. Schedule extra time for the visit. Allow for personal attention to your care needs once in the examination room. Friendly, nice staff and doctor puts you at ease. Bottom line: worth the wait!
Sisle
Sisle
21:49 26 Oct 23
Excellent service and staff i’ll let you feel relaxing and comfortable
kadine campbell
kadine campbell
21:01 23 Oct 23
I was given good advice about my blood circulation
Emma Bb
Emma Bb
17:04 08 Oct 23
Dr. Shams office is amazing. Whitney and Angela were AMAZING. Great sense of humor. Staff is WONDERFUL.
Sara Correa
Sara Correa
21:13 18 Sep 23
Nice office, personnel friendly, & caring, good informative information concerning my care.
Loretta Johnson
Loretta Johnson
21:26 22 Aug 23
Really like this doctor, talks in your language, just over all regular nice person.
Linda Thoomey
Linda Thoomey
22:03 21 Jul 23
I’m very satisfied of my visit for the first time, everyone was concerned about me, and Dr David was very patient to listen to my long health stories, after that He gave me good explanation for my problem, that was great 👍
Claude Jean Pierre
Claude Jean Pierre
22:38 18 Jul 23
Follow up to a procedure. Dr Mobley and his staff are great and always helpful
DanLiza Diehl
DanLiza Diehl
21:25 10 Jul 23
Dr Mobley was so helpful, informative and made me feel secure in making my future medical plan. Supportive and kind. Highly recommended.
Amanda L Browder
Amanda L Browder
15:57 23 Jun 23
Doctor was very thorough. Explaining what the procedure is all about. Tell me what I could realistically expect. Couldn’t have asked for a better consultation. Highly recommended if you have a prostate issue
John Buric
John Buric
16:26 15 Jun 23
I was very pleased and satisfied on how Dr. David Mobley examined me and explained everything on what I need to know regarding my condition. He’s very professional and knowledgeable in all aspects of his profession. I would highly recommend him to my other friends!
Celine Parcon
Celine Parcon
23:16 07 Jun 23
He puts his patients before himself, returning calls and e-mails quickly. Not only is he kind and considerate, he is an excellent physician. I had to have a procedure that requires me to be awake, and he talked me through it and kept me at ease. If I could give him more stars, I would.
Super friendly, tentative, once in the procedure rm the sx staff made you feel comfortable, easy,+ answered all questions. David mobley, MD answered all my questions, very informative, caring. I felt confident in his care
Thais Bini
Thais Bini
21:22 30 May 23
Great doctor. Everyone is so kind and caring. Great place to go
Joan Jurica
Joan Jurica
14:46 30 May 23
The best in Astoria I recommend Dr mobley and staff 100 percent
michaela1951
michaela1951
21:25 30 Mar 23
Knowledgeable , experienced, great bed side manners
mohamed hamed
mohamed hamed
10:09 30 Mar 23
The doctor was very nice and professional. He explained the tests that I need and why I need them.
Judith AndersonNeal
Judith AndersonNeal
22:12 27 Mar 23
This was the best experience I have had in such a long time and I have had quite a few procedures in the past both in patient and out including the procedure I was currently present for. No other surgeon has been so kind, transparent, and gentle. Not only did he personally come out beforehand to provide me with education on my procedure, but he talked me through every step of the way and made me feel so comfortable and relaxed. Not to mention his amazing staff! Despite being extremely nervous they kept me smiling and laughing throughout the whole process. 10/10 would recommend. Thank you so much guys!!
Riah L.
Riah L.
13:49 22 Mar 23
Excellent bedside manners and the procedure was a breeze.
sen-pei hsia
sen-pei hsia
18:26 20 Mar 23
Los mejores/ the best💖🙏
Ruthy Ochoa
Ruthy Ochoa
04:17 03 Mar 23
Although I didn’t meet with the doctor, the receptionist, assistant and nurse were great.
Theresa Gaines
Theresa Gaines
13:25 13 Feb 23
Every thing and the process are being done properly ..Terissa you are very Carey ..thank you so much every body are very polite and very professional.. Thank you so much to Dr.Mobley..God blessed you all .🙏🙏🙏👍
Remigio Ruda
Remigio Ruda
03:28 31 Jan 23
Very knowledgeable, personable and professional. I came to Dr. Mobley to correct another surgeons work and I was pleased with the outcome. There is a Hispanic woman that runs things in the O.R.She is great! The whole staff is wonderful and caring.Highly recommend
Lakesha Kingdom
Lakesha Kingdom
15:57 17 Jan 23
I had a wonderful PA take care of me, & the nurses were very sweet. I was happy with my visit
Aurora Anello
Aurora Anello
19:20 10 Jan 23
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